{"id":430,"date":"2026-08-14T01:01:23","date_gmt":"2026-08-14T01:01:23","guid":{"rendered":"http:\/\/www.imagerie-medicale-95.fr\/pharmacie\/?p=430"},"modified":"2026-08-14T01:01:23","modified_gmt":"2026-08-14T01:01:23","slug":"un-nouveau-traitement-contre-le-cancer-du-foie-entre-dans-une-phase-dinnovation-au-royaume-uni","status":"publish","type":"post","link":"https:\/\/www.imagerie-medicale-95.fr\/pharmacie\/un-nouveau-traitement-contre-le-cancer-du-foie-entre-dans-une-phase-dinnovation-au-royaume-uni\/","title":{"rendered":"Un nouveau traitement contre le cancer du foie entre dans une phase d\u2019innovation au Royaume-Uni"},"content":{"rendered":"

L\u2019entreprise BeOne Medicines a obtenu un \u2018passeport innovation\u2019 pour son m\u00e9dicament exp\u00e9rimental BGB\u2011B2033, un anticorps bisp\u00e9cifique d\u00e9velopp\u00e9 contre le carcinome h\u00e9patocellulaire, la forme la plus fr\u00e9quente du cancer du foie. Ce passeport permet d\u2019acc\u00e9l\u00e9rer le d\u00e9veloppement du traitement<\/a> et sa mise \u00e0 disposition pour les patients au Royaume-Uni, gr\u00e2ce \u00e0 un acc\u00e8s privil\u00e9gi\u00e9 \u00e0 une proc\u00e9dure d\u00e9di\u00e9e aux maladies graves ou invalidantes.<\/p>\n

Ce passeport est accord\u00e9 par l\u2019Agence britannique de r\u00e9gulation des m\u00e9dicaments (MHRA). BGB\u2011B2033 agit en ciblant deux \u00e9l\u00e9ments : la prot\u00e9ine GPC3, pr\u00e9sente en quantit\u00e9 \u00e9lev\u00e9e dans les cellules canc\u00e9reuses du foie, et le r\u00e9cepteur 4\u20111BB, qui stimule la r\u00e9ponse immunitaire. Le m\u00e9dicament est actuellement \u00e9tudi\u00e9 pour des patients atteints de formes avanc\u00e9es ou m\u00e9tastatiques de la maladie.<\/p>\n

James Harris, responsable par int\u00e9rim de BeOne Medicines pour le Royaume-Uni et l\u2019Irlande, a d\u00e9clar\u00e9 : \u00ab Les patients atteints de carcinome h\u00e9patocellulaire ont encore un pronostic sombre, ce qui rend n\u00e9cessaire le d\u00e9veloppement de nouvelles options th\u00e9rapeutiques. Nous pensons que BGB\u2011B2033 pourrait apporter un b\u00e9n\u00e9fice significatif \u00e0 ces patients. Nous sommes ravis de participer \u00e0 cette proc\u00e9dure d\u2019acc\u00e8s acc\u00e9l\u00e9r\u00e9, qui facilite une collaboration pr\u00e9coce avec les autorit\u00e9s sanitaires britanniques. Nous allons maintenant travailler en \u00e9troite collaboration avec la MHRA et ses partenaires pour faire avancer le d\u00e9veloppement de ce traitement exp\u00e9rimental. \u00bb<\/p>\n

Le passeport innovation permet aux d\u00e9veloppeurs de b\u00e9n\u00e9ficier d\u2019un accompagnement tout au long du d\u00e9veloppement du m\u00e9dicament. Il peut aussi donner acc\u00e8s \u00e0 des outils r\u00e9glementaires et scientifiques pour faciliter l\u2019arriv\u00e9e rapide du traitement aupr\u00e8s des patients.<\/p>\n

En 2026, l\u2019entreprise pr\u00e9voit de lancer un essai clinique mondial, potentiellement d\u00e9cisif pour une future autorisation de mise sur le march\u00e9. Aux \u00c9tats-Unis, BGB\u2011B2033 a d\u00e9j\u00e0 re\u00e7u les d\u00e9signations de \u2018Fast Track\u2019 et de \u2018m\u00e9dicament orphelin\u2019, acc\u00e9l\u00e9rant son \u00e9valuation.<\/p>\n

Au Royaume-Uni, environ 7 000 personnes sont diagnostiqu\u00e9es chaque ann\u00e9e avec un cancer du foie, dont 85 % sont des carcinomes h\u00e9patocellulaires. L\u2019incidence de cette maladie a augment\u00e9 de pr\u00e8s de 25 % au cours des dix derni\u00e8res ann\u00e9es. La majorit\u00e9 des patients (75 %) sont diagnostiqu\u00e9s \u00e0 un stade avanc\u00e9, avec un taux de survie \u00e0 cinq ans inf\u00e9rieur \u00e0 15 %.<\/p>\n","protected":false},"excerpt":{"rendered":"

L\u2019entreprise BeOne Medicines a obtenu un \u2018passeport innovation\u2019 pour son m\u00e9dicament exp\u00e9rimental BGB\u2011B2033, un anticorps bisp\u00e9cifique d\u00e9velopp\u00e9 contre le carcinome […]<\/p>\n","protected":false},"author":0,"featured_media":431,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"site-sidebar-layout":"default","site-content-layout":"","ast-site-content-layout":"default","site-content-style":"default","site-sidebar-style":"default","ast-global-header-display":"","ast-banner-title-visibility":"","ast-main-header-display":"","ast-hfb-above-header-display":"","ast-hfb-below-header-display":"","ast-hfb-mobile-header-display":"","site-post-title":"","ast-breadcrumbs-content":"","ast-featured-img":"","footer-sml-layout":"","ast-disable-related-posts":"","theme-transparent-header-meta":"","adv-header-id-meta":"","stick-header-meta":"","header-above-stick-meta":"","header-main-stick-meta":"","header-below-stick-meta":"","astra-migrate-meta-layouts":"default","ast-page-background-enabled":"default","ast-page-background-meta":{"desktop":{"background-color":"var(--ast-global-color-5)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"tablet":{"background-color":"","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"mobile":{"background-color":"","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""}},"ast-content-background-meta":{"desktop":{"background-color":"var(--ast-global-color-4)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"tablet":{"background-color":"var(--ast-global-color-4)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"mobile":{"background-color":"var(--ast-global-color-4)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""}},"footnotes":""},"categories":[414],"tags":[],"class_list":["post-430","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-nouvelles"],"_links":{"self":[{"href":"https:\/\/www.imagerie-medicale-95.fr\/pharmacie\/wp-json\/wp\/v2\/posts\/430","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.imagerie-medicale-95.fr\/pharmacie\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.imagerie-medicale-95.fr\/pharmacie\/wp-json\/wp\/v2\/types\/post"}],"replies":[{"embeddable":true,"href":"https:\/\/www.imagerie-medicale-95.fr\/pharmacie\/wp-json\/wp\/v2\/comments?post=430"}],"version-history":[{"count":1,"href":"https:\/\/www.imagerie-medicale-95.fr\/pharmacie\/wp-json\/wp\/v2\/posts\/430\/revisions"}],"predecessor-version":[{"id":439,"href":"https:\/\/www.imagerie-medicale-95.fr\/pharmacie\/wp-json\/wp\/v2\/posts\/430\/revisions\/439"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/www.imagerie-medicale-95.fr\/pharmacie\/wp-json\/wp\/v2\/media\/431"}],"wp:attachment":[{"href":"https:\/\/www.imagerie-medicale-95.fr\/pharmacie\/wp-json\/wp\/v2\/media?parent=430"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.imagerie-medicale-95.fr\/pharmacie\/wp-json\/wp\/v2\/categories?post=430"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.imagerie-medicale-95.fr\/pharmacie\/wp-json\/wp\/v2\/tags?post=430"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}